华东师范大学学报(自然科学版) ›› 2026, Vol. 2026 ›› Issue (4): 83-91.doi: 10.3969/j.issn.1000-5641.2026.04.009

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一种提示驱动的统一非配对磁共振图像转换方法

虞千迪, 方发明, 张桂戌*()   

  1. 华东师范大学 计算机科学与技术学院, 上海 200062
  • 收稿日期:2024-11-19 出版日期:2026-07-25 发布日期:2026-07-18
  • 通讯作者: 张桂戌 E-mail:gxzhang@cs.ecnu.edu.cn
  • 基金资助:
    国家重点研发计划 (2022ZD0161800); 国家自然科学基金 (62271203)

A prompt-driven unified unpaired magnetic resonance image translation method based on generative adversarial networks

Qiandi YU, Faming FANG, Guixu ZHANG*()   

  1. School of Computer Science and Technology, East China Normal University, Shanghai 200062, China
  • Received:2024-11-19 Online:2026-07-25 Published:2026-07-18
  • Contact: Guixu ZHANG E-mail:gxzhang@cs.ecnu.edu.cn

摘要:

合成缺失的对比度磁共振图像是一项关键且具有挑战性的任务. 为了在单个模型中实现多对比度转换, 现有方法通常构建具有辅助损失的隐式对比度共享空间, 并使用独热对比度编码调制转换过程. 本文提出了ProGAN, 这是一种利用生成对抗网络模型的提示驱动的统一非配对磁共振图像转换方法. 其中, ProGAN利用可学习提示与对比语言–图像预训练模型的对比度特定文本嵌入作为外部知识来生成动态提示, 为对比度转换提供高效而鲁棒的指导. 在两个公共多对比度磁共振数据集上开展的广泛实验表明, ProGAN在定量和定性上都实现了较先进的性能.

关键词: 多对比度磁共振图像, 非配对图像翻译, 生成对抗网络, 对比语言–图像预训练

Abstract:

Synthesizing magnetic resonance (MR) images for missing contrast is a critical and challenging task. Existing methods usually construct an implicit contrast-shared space with auxiliary loss and modulate the translation process with one-hot contrast code to achieve multi-contrast translation in a single model. We propose an effective method, ProGAN, which is a prompt-driven unified unpaired MR image translation method based on a generative adversarial network (GAN). ProGAN leverages learnable prompts and text embeddings from contrastive language-image pre-training (CLIP) as external knowledge to generate multi-level dynamic prompts, providing powerful and robust guidance on contrasts. Extensive experiments on two public multi-contrast MRI datasets showed that ProGAN achieved state-of-the-art performance both quantitatively and qualitatively.

Key words: multi-contrast magnetic resonance images, unpaired image translation, generative adversarial network, contrastive language-image pre-training (CLIP)

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