华东师范大学学报(自然科学版) ›› 2004, Vol. 2004 ›› Issue (3): 126-130.

• 生命科学 • 上一篇    下一篇

大鼠皮层AⅠ区神经元对纯音频率的反应特征

何德富1, 2, 陈福俊2, 周绍慈2   

  1. 1. 华东师范大学 环境科学系,上海 200062; 2. 华东师范大学 脑功能研究室,上海 200062
  • 收稿日期:2003-09-10 修回日期:2003-10-09 出版日期:2004-09-25 发布日期:2004-09-25
  • 通讯作者: 何德富

The Characteristics of the Acoustic Response of AⅠNeurons to the Frequency of Pure Tone

HE De-fu1,2, CHEN Fu-jun2, ZHOU Shao-ci2   

  1. 1.Department of environment; 2.Lab of brain function research, East China Normal University, Shanghai 200062,China
  • Received:2003-09-10 Revised:2003-10-09 Online:2004-09-25 Published:2004-09-25
  • Contact: HE De-fu

摘要: 使用微电极在体胞外记录方法研究了SD大鼠AⅠ区神经元对纯音频率的反应特征.实验结果显示,AⅠ区神经元调谐曲线分为“V”、“W”和“U”型,神经元的Q10和Q30值均随着神经元特征频率(CF)的增大而增加,不同CF神经元在AⅠ区具有分域特性,对高频敏感的神经元位于AⅠ区嘴侧,对低频敏感的神经元位于AⅠ区尾侧.结果还表明,随着AⅠ区神经元CF变大,神经元对特定的频率选择性能越强,频率响应范围变窄.CF的分域特性明显,反映了大鼠初级听皮层对声音频率信息编码遵循有规律的部位原则.

关键词: AⅠ区, 声反应, 调谐曲线, 特征频率, SD大鼠, AⅠ区, 声反应, 调谐曲线, 特征频率, SD大鼠

Abstract: The characteristics of the acoustic response of AⅠneurons to the frequency of pure tone were investigated with extracellularly recording. The experimental results showed that the tuning curves of AⅠneurons could be classified into “V”, “W”, and “U” types. Q10 values and Q30 values of AⅠneurons increased with increasing of the characteristic frequencies (CFs) of these neurons. The results also showed the topographical distribution of the CFs of neurons in AⅠcortex. Generally the neurons with high CFs laid in the rostral part of AⅠ, and the neurons with low CFs laid in its caudal part. These results indicated that AⅠneurons with high CFs had more powerful frequency selectivity ability than that with low CFs, and that the frequency range of acoustic response of AⅠneurons widened with increasing of CFs of these neurons. The topographical distribution of the CFs in AⅠindicated that the coding on frequency of sound stimulation accorded with the rule of place coding.

Key words: acoustic response, tuning curve, characteristic frequency, SD rat, AⅠcortex, acoustic response, tuning curve, characteristic frequency, SD rat

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