华东师范大学学报(自然科学版) ›› 2006, Vol. 2006 ›› Issue (2): 63-67.

• 生命科学 • 上一篇    下一篇

盘基网柄菌柄细胞分化过程中gp150分子的作用

侯连生   

  1. 华东师范大学 生命科学学院，上海 200062
  • 收稿日期:2004-12-23 修回日期:2005-03-09 出版日期:2006-03-25 发布日期:2006-03-25
  • 通讯作者: 侯连生

Function of gp150 in the Differentiation of Stalk Cell during〖WTHX〗 Dityosteliun Discoideum Development(Chinese)

HOU Lian-sheng   

  1. School of Life Science, East China Normal University, Shanghai 200062, China
  • Received:2004-12-23 Revised:2005-03-09 Online:2006-03-25 Published:2006-03-25
  • Contact: HOU Lian-sheng

摘要： 饥饿的盘基网柄菌进入多细胞发育期后，在细胞疏松结合阶段，gp150分子分布在多细胞体外周；在蛞蝓体阶段，gp150分子把蛞蝓体分成前孢子细胞区和前柄细胞区两个部分，在分化成柄细胞的区域内gp150分子的量逐渐增多.实验结果表明gp150分子与柄细胞分化有密切关系.

关键词: 盘基网柄菌, 柄细胞, 发育, 分化, gp150, 盘基网柄菌, 柄细胞, 发育, 分化, gp150

Abstract: Cells of Dictyostelium discoideum are trigged to undergo development when they are depleted their food source. Cell adhesion molecules play an important role in maintaining the integrity of cell aggregation and influencing subsequent cell-type differentiation and cell sorting. At the loose aggregation stage , gp150 was localized on the peripheral area of multicellular aggregation.At the slug stage, the prespore cell domain and prestalk cell domain were separated by the gp150 molecule, quantity of the gp150 molecule become to increase in the pretalk cell domain following Dictyostelium discoideum development. Thus the temporal of gp150 molecule expression and the special localization of gp150 molecule are related with the differentiation of stalk cells Dictyostelium discoideum development.

Key words: stalk cell, development, differentiation, gp150, Dictyostelium discoideum, stalk cell, development, differentiation, gp150

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