Journal of East China Normal University(Natural Sc ›› 2016, Vol. 2016 ›› Issue (2): 1-8.doi: 10.3969/j.issn.1000-5641.2016.02.001

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A review of the studies on melanin synthesis and whitening products

YE Xi-yun,ZHU Ping-ya   

  • Received:2015-07-01 Online:2016-03-25 Published:2016-07-25

Abstract: Due to environmental pollution and the increasing size of the ozone hole, more UV rays penetrate the atmosphere and reach the ground, which leads to skin pigmentation abnormalities. In this article, we reviewed the latest studies on melanin synthesis, mainly focusing on the regulation and related signal pathways with regard to tyrosinase, a vital rate-limiting enzyme involved in this process. Several critical factors affecting melanin synthesis were also presented, providing theoretical basis for screening melanin inhibitors. In addition, several new popular commercial whitening products and their property were discussed. All these information is benificial to draw the public’s attention to skin pigmentation disorder as well as proper care.

Key words: melanin, melanin synthesis, tyrosinase, regulation, whitening products

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