Environmental impacts and ecological risks of antibiotics and resistance genes in livestock and poultry farming

doi:10.3969/j.issn.1000-5641.2024.06.013

Abstract

Abstract:

This article provides a review of the impacts and potential ecological risks of antibiotics and resistance genes in livestock and poultry farming environments. Through systematic research on the relevant literature, the use of antibiotics in livestock and poultry farming in different regions was summarized. The study found that the residual concentrations of antibiotics and resistance genes in soil after returning livestock and poultry manure to the field varied due to factors such as manure type, region, farm scale, and management measures. Moreover, the migration and transformation of antibiotics and resistance genes in soil are influenced by the soil type and fertilization methods. This study specifically explored the impact of the spreading of resistance genes through mechanisms such as horizontal gene diffusion by soil microorganisms and systematically elucidated the ecological risks of antibiotics and resistance genes. Finally, based on the current pollution situation of returning livestock manure to the field, a summary and outlook on reducing the accumulation and diffusion of antibiotics and resistance genes in the environment were prepared. The work is expected to provide strong support for a comprehensive understanding of the environmental impacts and ecological risks of antibiotics and resistance genes in livestock and poultry farming.

Key words: antibiotic, antibiotic resistance gene, livestock manure, ecological risk

CLC Number:

X713

Wenan HU, Cheng SHEN, Huilun SUN, Qiang WANG, Min LIU. Environmental impacts and ecological risks of antibiotics and resistance genes in livestock and poultry farming[J]. Journal of East China Normal University(Natural Science), 2024, 2024(6): 151-160.

Figures/Tables 3

Table 1

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Table 3

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类别	抗生素
喹诺酮类	环丙沙星、恩诺沙星、马波沙星、达诺沙星、地氟沙星、沙拉沙星、氟喹诺酮、诺氟沙星、氟喹诺酮酸、奥昔酸
四环素类	强力霉素、土霉素
氨基糖苷类	庆大霉素、阿米卡星
大环内酯类	泰乐菌素、红霉素
磺胺类	磺胺嘧啶、甲氧苄啶-磺胺甲恶唑
林可酰胺类	林可霉素
头孢菌素类	头孢洛辛、头孢噻呋
β-内酰胺类	氨苄青霉素、青霉素 G、克洛沙星、二氯氨苄青霉素、头孢氨苄

地区	抗生素种类	浓度	粪肥种类	参考文献
徐州	磺胺类	19.95 μg/kg	马粪	[25]
	磺胺类	8.10 μg/kg	鹅粪
	喹诺酮类	18.20 μg/kg	牛粪
	喹诺酮类	104.55 μg/kg	鹅粪
	大环内酯类	167.70 μg/kg	猪粪
	大环内酯类	10.20 μg/kg	牛粪
北京	四环素类	1377.40 μg/kg	猪粪	[26]
北京	喹诺酮类	27.28 μg/kg	牛粪	[26]
浙北	四环素类	4.37 mg/kg	猪粪	[27]
		2.18 mg/kg	鸡粪
		1.07 mg/kg	牛粪
京津冀	四环素类	19.34 mg/kg	猪粪	[16]
	四环素类	9.87 mg/kg	鸡粪
	磺胺类	-	猪粪
	磺胺类	-	鸡粪
	β-内酰胺类	-	猪粪
	β-内酰胺类	-	鸡粪
重庆	四环素类	167.30 mg/kg	猪粪	[29]
重庆	四环素类	37.40 mg/kg	鸡粪	[29]

地区	ARGs	ARGs相对丰度	粪肥种类	参考文献
河北	多种ARGs	4.99 × 10^–2	猪粪	[34]
河北	多种ARGs	1.36 × 10^–1	鸡粪
天津	多种ARGs	1.89 × 10^–2	猪粪
天津	多种ARGs	4.45 × 10^–2	鸡粪
广东	多种ARGs	1.87 ~ 8.88 copies/16S rRNA	肉鸡粪	[35]
广东	多种ARGs	0.07 ~ 2.96 copies/16S rRNA	蛋鸡粪	[35]
杭州	磺胺类	1.09 × 10^–2 ~ 1.32 × 10^–1	鸭粪	[36]
		1.09 × 10^–2 ~ 1.32 × 10^–1	鸡粪
		3.26 × 10^–4 ~ 2.81 × 10^–3	猪粪
		3.26 × 10^–4 ~ 2.81 × 10^–3	羊粪

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