Journal of East China Normal University(Natural Sc ›› 2006, Vol. 2006 ›› Issue (2): 88-92.

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15α-Hydroxylation of 13-ethy1-estr-4-ene-3,17-dione Using Immobilized Penicillium raistrickii by Calcium Alginate gel Embedding Methd(Chinese)

LI Jun, GENG Xu, ZHANG Pei-jun, WU Zi-rong   

  1. Shool of Life Science, East China Normal University, Shanghai 200062, China
  • Received:2004-12-29 Revised:2005-04-13 Online:2006-03-25 Published:2006-03-25
  • Contact: WU Zi-rong

Abstract:

15α-hydroxylation of 13-ethyl-estr-4-ene-3,17-dione using immobilized Penicillium raistrickii entrapped in calcium alginate gel was studied. The conversion conditions, which affected hydroxylation such as substrate concentration, the time to add substrate, conversion duration, were investigated. The results show that, the immobilized Penicillium raistrickii can be utilized repeatedly five times with no obvious decline of hydroxylation ability.

Key words: 15α-hydroxylation, immobilized method, Penicillium raistrickii, 15α-hydroxylation, immobilized method

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