Journal of East China Normal University(Natural Sc ›› 2006, Vol. 2006 ›› Issue (2): 1-6.

• Article •     Next Articles

Syntheses and Biological Activity of Novel Heteroretinoids(Chinese)

CHEN Zhen, WANG Jing, XU Zi-jin, ZOU Xin-zhuo   

  1. Department of Chemistry, East China Normal University, Shanghai 200062, China
  • Received:2005-04-07 Revised:2005-04-22 Online:2006-03-25 Published:2006-03-25
  • Contact: ZOU Xin-zhuo

Abstract:

Syntheses of three novel heteroretinoids were reported. Novel heteroretinoids were 5-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-3-pyrazole carboxylic acid, 2-Methyl -5-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-furan-3-carboxylic acid, 1-Butyl -2-methyl-5-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-1H-pyrrole-3-carboxylic acid.The results of biological test indicated that these compounds possessed some growth inhibition effects in leukemia cells.

Key words: heterocycle, synthesis, biological activity, heteroretinoid, heterocycle, synthesis, biological activity

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