With the popularization of university information system applications and the increase in their usage frequency, teachers and students have higher requirements for data consistency, accuracy, timeliness, and completeness. The original data synchronization scheme using extensible markup language (XML) for data synchronization has the disadvantages of low synchronization efficiency and difficulty of expansion. The open-source tool, DataX, can complete data synchronization between various heterogeneous databases without damaging the source database. This study used DataX to improve the original data synchronization scheme and proposed different data synchronization schemes for various business requirements and application scenarios in the foundation of university postgraduate information system construction. At the same time, in view of the shortcomings of DataX in which only one read can do one write during the start-up and execution, the method where one read can do multiple writes was designed. The comparison experiment shows that the optimized scheme can improve data synchronization efficiency, has better scalability, and can meet the data synchronization requirements of universities.